References

1. Questions and answers about FDA's enforcement action regarding unapproved hydrocodone drug products. Available at: www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2007
/ucm108997.htm. Accessed July 30, 2008.

2. American Society of Health-System Pharmacists. AHFS Drug Information (AHFS DI) 2008 Edition. Bethesda, MD: American Society of Health-System Pharmacists; 2008.

3. TussiCaps^® Prescribing Information

4. Hurst M. Oral medication dispensers in clinical research. J Clin Res Best Pract. 2006;2. Available at: www.firstclinical.com/journal/2006/0609_Oral_Dispensers.pdf. Accessed July 11, 2007.

5. Mattar ME, Markello J, Yaffe SJ. Inadequacies in the pharmacologic management of ambulatory children. J Pediatr. 1975;87:137-41. DOI 10.1016/S0022-3476(75)80090-4.

6. Hyam E, Brawer M, Herman J, Zvieli S. What's in a teaspoon? Underdosing with acetaminophen in family practice. Fam Pract. 1989;6:221-3.

7. Sobhani P, Christopherson J, Ambrose PJ, Corelli RL. Accuracy of Oral Liquid Measuring Devices: Comparison of Dosing Cup and Oral Dosing Syringe. Ann Pharmacother. 2008;42:46-52.

8. Fernandez CV, Gillis-Ring J. Strategies for the prevention of medical error in pediatrics. J Pediatr 2003;143:155-62.

9. Survey conducted online by Harris Interactive for Covidien between July 30 and August 1, 2008, among 932 US adults. No estimates of theoretical sampling error can be calculated; a full methodology is available. Data on file.

10. French CT, Irwin RS, Curley FJ, Krikorian CJ. Impact of Chronic Cough on Quality of Life. Arch Intern Med. 1998;158:1657-1661.

IMPORTANT RISK INFORMATION
TussiCaps^® (hydrocodone polistirex and chlorpheniramine polistirex) extended-release capsules are indicated for relief of cough and upper respiratory symptoms associated with allergy or cold in adults and children 6 years of age and older.

TussiCaps^® is contraindicated in the presence of known allergy or sensitivity to hydrocodone or chlorpheniramine. The most common adverse reactions associated with TussiCaps^® are sedation, drowsiness, and mental clouding, which may impair the mental and/or physical abilities required for potentially hazardous tasks.